Bioremediation a process that utilizes biological agents to detoxify and restore polluted environments has gained significant attention in recent years. Among various biological agents acidic protease enzymes have shown promising potential in the degradation of organic waste, particularly in acidic environments. This review paper explores the application of acidic protease enzymes in waste management, highlighting their mechanisms, sources, and effectiveness in bioremediation processes. The paper also discusses the challenges and future perspectives of utilizing acidic protease enzymes for environmental sustainability. Environmental impacts from industrial, agricultural and urban activities pose significant challenges to ecosystems and human health. Traditional waste management strategies often fail to adequately address these pollution issues. Bioremediation using biological products or their derivatives provides a sustainable and environmentally friendly way to clean up contaminated environments this paper explores the potential of acid protease enzymes in environmental bioremediation for waste management. Acid proteases, which can degrade proteins under acidic conditions, hold promise for breaking down pollutants in various wastes The paper reviews the properties and functions of acidic protease enzymes, discusses their applications in industrial effluents, agricultural effluents sources and treatment of contaminated soils Cases are analyzed and examples of their successful applications are presented to demonstrate the effectiveness of acid protease enzymes in the bioremediation under investigation. Challenges and future directions for the use of acidic protease enzymes for weed management are discussed, emphasizing the importance of combining enzyme-based bio treatment with other mitigation strategies for effective pollution control the emphasis.