Traditional medicine, rooted in centuries of use, remains a cornerstone of healthcare in many developing countries, where plants have long been valued for their medicinal properties. As global interest in the pharmacological potential of medicinal plants continues to rise, research has increasingly focused on their role as rich sources of bioactive compounds, particularly those with antimicrobial properties. Plant extracts are at the forefront of efforts to identify new agents capable of combating the growing issue of antimicrobial resistance (AMR), which has led to the rise of multi-resistant bacterial strains. Among the vast biodiversity of plants present in the Gadchiroli district in Maharashtra, India, Bauhinia purpurea has also been traditionally used by local tribes for its ethnomedicinal properties. The present study investigates the antimicrobial potential of various phytochemical extract fractions of Bauhinia purpurea (methanol, hexane, acetone extracts) against common bacterial pathogens. This study highlights the importance of ethnobotanical knowledge and the therapeutic potential of plants in addressing the growing challenge of antibiotic resistance.