Gamma oryzanol is a dietary substance primarily derived from rice bran, a byproduct of rice milling, where it makes up about 1-2% of rice bran oil. It can also be extracted from wheat germ oil, corn oil, and certain fruits and vegetables. This crystalline, white, and water-insoluble compound is consumed as a nutraceutical—products that offer health benefits along with nutritional value. γ-Oryzanol boosts immune responses against pathogens and helps manage hyperlipidemia by reducing LDL (bad cholesterol) and triglycerides in the blood. It acts as an antioxidant by neutralizing free radicals produced during oxidative metabolism, thus preventing cellular damage. Additionally, γ-oryzanol has anti-cancer and anti-inflammatory properties, and it can influence hormonal health. Its chemical structure includes ferulic acid, which has notable effects in the cosmetic industry, such as inhibiting collagenase, absorbing UV rays, and alleviating itching. For optimal health benefits and to address specific conditions, γ-oryzanol should be consumed in recommended amounts as advised by a healthcare professional.