FORMULATION, OPTIMIZATION, AND CHARACTERIZATION OF PHOSPHOLIPIDS ENCAPSULATED MANGIFERIN TO IMPROVE ITS ANTI-DIABETIC ACTIVITY

Abstract

Diabetes has emerged as the world's most significant issue in the modern era. The metabolisms could be affected. This imbalance may impair insulin secretion and function. In order to increase the solubility of Mangiferin extracts' phytoconstituents, the current work set out to create and characterise phytosomes of those extracts. Its oral absorption and bioavailability are constrained by the phytoconstituents' poor solubility and rapid rate of dissolution. The solvent evaporation approach was utilised to create phytosomes using the standardised extracts of mangiferin. The optimised phytosomes were evaluated for a number of parameters.