Formulation And Evaluation Of Felodipine Bilayered Tablet

Abstract

Hypertension is a major risk for Cardiovascular and stroke complications. The good permeability and the poor water solubility (BCS class II) as well as short biological half-life characteristics of Felodipine selected as a drug candidate for bilayer preparations. Felodipine belongs to dihydropyridine derivative, which acts as a calcium channel blocker, used as an anti-hypertensive drug. Here the aim was to combine two Felodipine which are available in the market as single dose immediate release tablets. So the patients don’t have to take two tablets. It will also reduce the cost of the tablet as immediate- release tablet or extended- release tablet.