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REVIEW ARTICLE
Year : 2021  |  Volume : 10  |  Issue : 1  |  Page : 1-5

Trace element status and human endocrine health: A perspective


1 Assistant Professor, Department of Chemistry, BVDU's Poona College of Pharmacy, Pune, Maharashtra, India
2 BVDU's, R and D Centre in Pharmaceutical Sciences and Applied Chemistry, Poona College of Pharmacy, Pune, Maharashtra, India

Correspondence Address:
Dr. Deepti Gholap Khanvilkar
Assistant. Professor, Department of Chemistry, BVDU's Poona College of Pharmacy, Pune, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijfans.ijfans_2_21

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The presence of trace elements is vital for the smooth functioning of the human body. Although trace elements such as Cr, Cu, Fe, I, Mn, Ni, Se, Zn are present in low concentrations, they are considered as the building blocks of life, participating actively in regulating many biochemical processes. The endocrine system influences every cell in the human body to maintain equilibrium at the cellular level. Imbalance in the homeostasis of hormone production, secretion, manifests in the development of endocrine abnormalities. The specific objective of this article is to perform a comprehensive, detailed evaluation of the adequacy of current research undergoing risk assessment of endocrine-related disorders and its association with trace elements. In this review, we have studied >100 research and review publications on the aforementioned topic. After a thorough investigation it has come to our notice, that although not many, there are a few studies undertaking the investigation of the individual influence of a particular trace element on a focused pathological hormonal disorder. However, there are only a handful of studies investigating the effect of the multiple trace elements and their combined effect on the molecular as well as cellular functions of the human endocrine system.


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