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Year : 2015  |  Volume : 4  |  Issue : 1  |  Page : 149-157

Fenugreek: A treasure of bioactive compounds with promising antidiabetic potential

Biochemistry and Molecular Biotechnology Laboratory, SKUAST-K, Shalimar Campus, Jammu and Kashmir, India

Correspondence Address:
Imtiyaz Murtaza
Biochemistry and Molecular Biotechnology Laboratory, SKUAST-K, Shalimar Campus, Jammu and Kashmir
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Source of Support: None, Conflict of Interest: None

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Diabetes is a major health problem predisposing to markedly increased complications. Despite the numerous preventative strategies and armoires of medication, the management of diabetes remains grossly unsatisfactory. Diabetes is an oxidative stress related disorder and is emerging as a pandemic. The immediate need is to identify novel food based bioactive agents or drugs for curing or preventing diabetes, with comparatively fewer side effects. Plant secondary metabolites have long been known to have health benefits against various oxidative stress related diseases including diabetes. One of the most promising vegetable providing treasures of such secondary metabolites is fenugreek. This paper presents information on bioactive compounds of fenugreek and its strong anti-diabetic power. The herb have an enormous potential to prevent or cure diabetes more than other plant species especially due to the presence of unique chemical constituents including quercetin, diosgenin, trignolline, galactomanin and unusual amino acid 4 hydroxy isolucine. However, due to lack of enough scientific or clinical studies the use of fenugreek as hypoglycaemic official'drug remains to be explored. It is proposed that a close attention be paid for preventive and curative properties of this potent herb against diabetes and its complications.

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